Nootropic
Vinpocetine
Also known as: Ethyl apovincaminate
Semi-synthetic compound from periwinkle enhancing cerebral blood flow and neuroprotection.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Primary uses
- Cerebral blood flow
- Memory
- Neuroprotection
- Hearing
How it works
- Increases cerebral blood flow
- Inhibits PDE1
- Anti-inflammatory in brain
Dosage
- Typical range
- 5-20 mg daily
- Timing
- With meals
- With food
- Yes, improves absorption
- Duration
- Acute and long-term effects
- Special populations
- Cognitive decline, cerebrovascular
Forms
- Capsules
Safety
Common side effects
- Headache
- Flushing
- Sleep disturbances
Contraindications
- Bleeding disorders
Evidence notes
Enhances brain circulation
Grade B: Some human trials support key claims; further confirmation needed.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.