Nootropic
Lithium Orotate
Also known as: Lithium orotate
Microdose lithium for neuroprotection and mood stability. Much lower dose than psychiatric lithium.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Primary uses
- Neuroprotection
- Mood stability
- BDNF support
- Longevity
How it works
- Increases BDNF
- Inhibits GSK-3
- Neuroprotective at low doses
Dosage
- Typical range
- 1-5 mg elemental lithium daily
- Timing
- Any time
- With food
- Optional
- Duration
- Long-term use
- Special populations
- Mood support, neuroprotection
Forms
- Low-dose tablets
Safety
Common side effects
- Minimal at low doses
Contraindications
- Kidney disease
- Thyroid disorders
Evidence notes
Microdose lithium for brain health
Grade B: Some human trials support key claims; further confirmation needed.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.