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Herbal Extract

Supercritical CO2 Boswellia sacra Extract

Also known as: Boswellia sacra, Frankincense extract, Boswellia resin extract, CO2 Boswellia extract

B
Evidence

Boswellia sacra is a tree resin traditionally used in Ayurvedic and traditional medicine, with modern research suggesting potential anti-inflammatory and joint-support properties via boswellic acid compounds. Supercritical CO2 extraction concentrates these active constituents while avoiding solvent residues.

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Primary uses

  • Joint health and mobility
  • Anti-inflammatory support
  • Cognitive/mood support
  • Respiratory health

How it works

  • Boswellic acids inhibit NF-κB pathway and reduce pro-inflammatory cytokines
  • 5-Loxo inhibition reduces leukotriene production
  • Antioxidant activity from polyphenolic compounds

Dosage

Typical range
300–600 mg daily (extract; equivalent to 1.5–3 g crude resin)
Timing
With meals for better absorption
With food
Recommended with food or fat to enhance bioavailability
Duration
Typical studies use 8–12 weeks; benefits may accumulate over time
Special populations
Pregnant/nursing women should consult a healthcare provider before use

Forms

  • Capsules· 70/100
  • Powder· 70/100
  • Liquid extract· 70/100

Safety

Common side effects

  • Mild gastrointestinal upset
  • Rare allergic reactions (tree resin sensitivity)

Contraindications

  • Allergy to Boswellia or related resins
  • Pregnancy and lactation (limited safety data)

Products containing Supercritical CO2 Boswellia sacra Extract

Top-scoring supplements in our catalog that list Supercritical CO2 Boswellia sacra Extract on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

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Evidence notes

Boswellia sacra and frankincense extracts have multiple RCTs showing modest benefits for joint comfort and function, with consistent mechanistic support. Supercritical CO2 extraction is a premium form but lacks direct comparative RCT data versus standard extracts; evidence applies to boswellia genus generally.

Grade B: Some human trials support key claims; further confirmation needed.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.