Herbal Extract
Supercritical CO2 Boswellia sacra Extract
Also known as: Boswellia sacra, Frankincense extract, Boswellia resin extract, CO2 Boswellia extract
Boswellia sacra is a tree resin traditionally used in Ayurvedic and traditional medicine, with modern research suggesting potential anti-inflammatory and joint-support properties via boswellic acid compounds. Supercritical CO2 extraction concentrates these active constituents while avoiding solvent residues.
Primary uses
- Joint health and mobility
- Anti-inflammatory support
- Cognitive/mood support
- Respiratory health
How it works
- Boswellic acids inhibit NF-κB pathway and reduce pro-inflammatory cytokines
- 5-Loxo inhibition reduces leukotriene production
- Antioxidant activity from polyphenolic compounds
Dosage
- Typical range
- 300–600 mg daily (extract; equivalent to 1.5–3 g crude resin)
- Timing
- With meals for better absorption
- With food
- Recommended with food or fat to enhance bioavailability
- Duration
- Typical studies use 8–12 weeks; benefits may accumulate over time
- Special populations
- Pregnant/nursing women should consult a healthcare provider before use
Forms
- Capsules· 70/100
- Powder· 70/100
- Liquid extract· 70/100
Safety
Common side effects
- Mild gastrointestinal upset
- Rare allergic reactions (tree resin sensitivity)
Contraindications
- Allergy to Boswellia or related resins
- Pregnancy and lactation (limited safety data)
Evidence notes
Boswellia sacra and frankincense extracts have multiple RCTs showing modest benefits for joint comfort and function, with consistent mechanistic support. Supercritical CO2 extraction is a premium form but lacks direct comparative RCT data versus standard extracts; evidence applies to boswellia genus generally.
Grade B: Some human trials support key claims; further confirmation needed.
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