Herbal Extract
Supercritical CO2 Boswellia sacra Extract
Also known as: Boswellia sacra, Frankincense extract, Boswellia resin extract, CO2 Boswellia extract
Boswellia sacra is a tree resin traditionally used in Ayurvedic and traditional medicine, with modern research suggesting potential anti-inflammatory and joint-support properties via boswellic acid compounds. Supercritical CO2 extraction concentrates these active constituents while avoiding solvent residues.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Primary uses
- Joint health and mobility
- Anti-inflammatory support
- Cognitive/mood support
- Respiratory health
How it works
- Boswellic acids inhibit NF-κB pathway and reduce pro-inflammatory cytokines
- 5-Loxo inhibition reduces leukotriene production
- Antioxidant activity from polyphenolic compounds
Dosage
- Typical range
- 300–600 mg daily (extract; equivalent to 1.5–3 g crude resin)
- Timing
- With meals for better absorption
- With food
- Recommended with food or fat to enhance bioavailability
- Duration
- Typical studies use 8–12 weeks; benefits may accumulate over time
- Special populations
- Pregnant/nursing women should consult a healthcare provider before use
Forms
- Capsules· 70/100
- Powder· 70/100
- Liquid extract· 70/100
Safety
Common side effects
- Mild gastrointestinal upset
- Rare allergic reactions (tree resin sensitivity)
Contraindications
- Allergy to Boswellia or related resins
- Pregnancy and lactation (limited safety data)
Products containing Supercritical CO2 Boswellia sacra Extract
Top-scoring supplements in our catalog that list Supercritical CO2 Boswellia sacra Extract on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
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Evidence notes
Boswellia sacra and frankincense extracts have multiple RCTs showing modest benefits for joint comfort and function, with consistent mechanistic support. Supercritical CO2 extraction is a premium form but lacks direct comparative RCT data versus standard extracts; evidence applies to boswellia genus generally.
Grade B: Some human trials support key claims; further confirmation needed.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.