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SIBO Treatment Stack

Also known as: Herbal SIBO protocol, Natural antimicrobials

B
Evidence

Herbal antimicrobial protocol: Berberine, Oregano Oil, and Neem/Allicin for small intestinal overgrowth.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

  • SIBO treatment
  • Antimicrobial
  • Gut dysbiosis

How it works

  • Multi-herb antimicrobial
  • Targets small intestinal bacteria
  • Alternative to rifaximin

Dosage

Typical range
Berberine 500mg 3x + Oregano oil 200mg 2x + Neem 900mg or Allicin 450mg 2x daily
Timing
With meals
With food
Yes
Duration
4-6 weeks, may repeat
Special populations
Diagnosed SIBO

Forms

  • Separate supplements

Safety

Common side effects

  • Die-off reactions
  • GI upset
  • Nausea

Contraindications

  • Pregnancy
  • See individual herbs

Evidence notes

Herbal alternative to antibiotics for SIBO

Grade B: Some human trials support key claims; further confirmation needed.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.