Stack

Adrenal Support Stack

Also known as: Adrenal stack, HPA axis stack, Stress support stack

Evidence

Comprehensive adrenal support: Adaptogens (Rhodiola, Ashwagandha), B5, Vitamin C, Holy Basil.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

Adrenal support
Stress resilience
HPA axis balance

How it works

Multi-mechanism adrenal support
Adaptogenic balance
Nutrient support
HPA axis modulation

Dosage

Typical range: Rhodiola 200-400mg AM + Ashwagandha 300-600mg PM + B5 250-500mg + Vitamin C 500-1000mg + Holy Basil 300mg
Timing: Stimulating adaptogens AM, calming PM
With food: Mixed
Duration: Cycle adaptogens, nutrients ongoing
Special populations: Chronic stress, burnout, adrenal support

Forms

Separate supplements

Safety

Common side effects

See individual components

Contraindications

See individual components

Evidence notes

Evidence-based comprehensive adrenal support

Grade B: Some human trials support key claims; further confirmation needed.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.