Nootropic
Polygala tenuifolia
Also known as: Yuan Zhi, Chinese senega, Polygala tenuifolia 20:1 Extract, Thin-leaf Milkwort
A traditional Chinese herb used for centuries to support memory, cognitive clarity, and emotional balance; the 20:1 extract represents a concentrated form standardized to preserve bioactive constituents. Modern research suggests potential nootropic and anxiolytic properties, though human clinical evidence remains limited.
Primary uses
- Memory
- Mood
- BDNF support
- Anti-anxiety
- Memory and learning enhancement
- Cognitive clarity and focus
- Mood and emotional stability
- Sleep quality
- Stress and anxiety reduction
How it works
- May increase BDNF
- Anti-inflammatory in brain
- Traditional memory tonic
Dosage
- Typical range
- 100-300 mg extract daily
- Timing
- Any time
- With food
- Optional
- Duration
- Weeks for effects
- Special populations
- Memory, mild anxiety
Forms
- Root extract
- 20:1 dry extract· 70/100
- Raw root powder· 70/100
- Liquid extract· 70/100
- Standardized extracts (variable standards)· 70/100
Safety
Common side effects
- GI upset
Contraindications
- None known
Evidence notes
Traditional cognitive herb
Grade B: Some human trials support key claims; further confirmation needed.
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