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Mood Support

PMS Mood Support Stack

Also known as: B6 + Magnesium + Calcium + Vitex

B
Evidence

PMS mood and symptom support: B6 + Magnesium + Calcium + Chasteberry.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

  • PMS symptoms
  • Mood
  • Cramps
  • Hormone balance

How it works

  • B6 for neurotransmitters
  • Magnesium for cramps
  • Calcium for symptoms
  • Vitex for hormones

Dosage

Typical range
50-100mg B6 + 200-400mg Mg + 500-1000mg Ca + 20-40mg Vitex
Timing
Daily, especially luteal phase
With food
Yes
Duration
2-3 cycles for full effect
Special populations
PMS sufferers

Forms

  • Separate supplements

Safety

Common side effects

  • B6 neuropathy high dose
  • GI upset

Contraindications

  • Hormone-sensitive conditions
  • Fertility treatment

Evidence notes

Components studied for PMS

Grade B: Some human trials support key claims; further confirmation needed.

Related in Mood Support

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.