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Antioxidant

NAC (N-Acetyl Cysteine)

Also known as: N-Acetyl Cysteine, N-Acetylcysteine, N-Acetyl-L-Cysteine, N-Acetyl Cysteine (NAC) - Detox Focus

A
Evidence

Precursor to glutathione, the body's master antioxidant. Supports liver, respiratory, and mental health.

Primary uses

  • Glutathione support
  • Liver health
  • Respiratory health
  • Mental health
  • Glutathione production
  • Liver detox
  • Mucolytic
  • Acetaminophen antidote
  • Ovulation
  • Insulin sensitivity
  • Antioxidant
  • PCOS support

How it works

  • Rate-limiting precursor to glutathione
  • Mucolytic (thins mucus)
  • Modulates glutamate
  • Acetaminophen antidote

Dosage

Typical range
600-1800 mg daily
Timing
Divided doses, away from food
With food
Away from food for glutathione; with food OK for respiratory
Duration
Safe long-term
Special populations
Liver support, respiratory, OCD/addiction

Forms

  • Capsules
  • Powder
  • Effervescent
  • IV
  • Sustained-release

Safety

Common side effects

  • GI upset
  • Sulfur smell/taste

Contraindications

  • Caution active cancer treatment

Evidence notes

Well-studied glutathione precursor

Grade A: Multiple well-designed human trials support the main claims.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.