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Amino Acid

Mucuna pruriens Extract (Seed) - 15% L-DOPA

Also known as: Velvet Bean, L-DOPA, Levodopa, Mucuna pruriens seed

B
Evidence

A legume extract standardized to contain 15% L-DOPA, a direct precursor to dopamine. Traditionally used in Ayurvedic medicine for mood, motivation, and motor function support.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

  • Dopamine support
  • Mood and motivation
  • Motor function
  • Sexual function
  • Athletic performance

How it works

  • Direct precursor to dopamine neurotransmitter
  • Crosses blood-brain barrier
  • Supports motivation and reward pathways

Dosage

Typical range
500-1500 mg daily (providing ~75-225 mg L-DOPA)
Timing
Morning to early afternoon (avoid evening due to stimulating effects)
With food
Take with light food to minimize nausea; avoid large meals which can interfere with absorption
Duration
Effects typically noticed within 2-4 weeks; tolerance may develop with long-term daily use
Special populations
Caution in individuals with cardiovascular disease; may interact with psychiatric medications

Forms

  • Extract· 70/100
  • Capsule· 70/100

Safety

Common side effects

  • Nausea
  • Dizziness
  • Headache
  • Vivid dreams or sleep disturbances

Contraindications

  • Uncontrolled hypertension
  • Recent heart attack or unstable angina
  • Melanoma or suspicious skin lesions
  • Concurrent MAOIs or carbidopa/levodopa therapy

Evidence notes

Good evidence for L-DOPA in Parkinson's disease; emerging evidence for mood and motivation in healthy individuals. 15% standardization is meaningful; however, bioavailability can vary.

Grade B: Some human trials support key claims; further confirmation needed.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.