Mineral
MSM (Sulfur Source)
Also known as: Methylsulfonylmethane, Organic sulfur
Organic sulfur for connective tissue, detoxification, and anti-inflammatory effects.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Primary uses
- Sulfur source
- Joint health
- Detox support
- Connective tissue
How it works
- Sulfur donor
- Anti-inflammatory
- Supports glutathione
Dosage
- Typical range
- 1-6g daily
- Timing
- Any time
- With food
- Optional
- Duration
- Safe long-term
- Special populations
- Joint issues, detox support
Forms
- Powder
- Capsules
- OptiMSM
Safety
Common side effects
- GI upset
- Headache initially
Contraindications
- None
Evidence notes
Organic sulfur compound
Grade B: Some human trials support key claims; further confirmation needed.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.