Nootropic

Modafinil (Informational)

Also known as: Provigil, Alertec

Evidence

Prescription wakefulness agent used off-label for cognitive enhancement. Requires prescription in most countries.

Primary uses

Wakefulness
Focus
Cognitive enhancement

How it works

Histamine and orexin modulation
Dopamine reuptake inhibition
Promotes wakefulness without typical stimulant effects

Dosage

Typical range: 100-200 mg (by prescription)
Timing: Morning
With food: Optional
Duration: As prescribed
Special populations: Narcolepsy, shift work (FDA approved)

Forms

Tablet

Safety

Common side effects

Headache
Nausea
Insomnia
Anxiety

Contraindications

Heart conditions
History of psychosis

Evidence notes

Prescription medication - well-studied

Grade A: Multiple well-designed human trials support the main claims.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.