Mineral
Manganese (as Manganese Bisglycinate Chelate)
Also known as: Manganese Glycinate, Chelated Manganese, Mn
Manganese is an essential trace mineral involved in bone formation, metabolism, and antioxidant enzyme function (manganese superoxide dismutase). The bisglycinate chelate form is designed for enhanced absorption compared to inorganic salts.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Manganese (as Manganese Bisglycinate Chelate) product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Thorne Advanced Nutrients | 88 A | $2.40 |
| 2 | Thorne Basic Nutrients 2/Day | 88 A | $0.60 |
| 3 | Thorne Basic Prenatal | 88 A | $1.23 |
| 4 | Thorne Men's Multi 50+ | 88 A | $1.87 |
| 5 | Pure Encapsulations Glucosamine Chondroitin with Manganese | 87 A | $0.54 |
| 6 | Garden of Life Vitamin Code 50 & Wiser Women | 87 A | $1.01 |
| 7 | Thorne MediClear-SGS™ - Vanilla | 86 A- | $2.10 |
| 8 | Transparent Labs Multivitamin | 86 A- | $1.33 |
| 9 | Seed AM-02™ Energy + Focus Supplement | 86 A- | $1.17 |
| 10 | Garden of Life Organics Women's Multi 40+ | 86 A- | $1.07 |
| 11 | Garden of Life Vitamin Code Raw One for Men | 86 A- | $0.41 |
| 12 | Garden of Life Organics Men's Multi | 86 A- | $1.16 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Manganese (as Manganese Bisglycinate Chelate) should I take?
The typical range is 1-5 mg daily. Safe for long-term supplementation
When should I take Manganese (as Manganese Bisglycinate Chelate)?
With meals. Recommended; enhances absorption.
Which form of Manganese (as Manganese Bisglycinate Chelate) is best?
Bisglycinate Chelate.
Is Manganese (as Manganese Bisglycinate Chelate) safe?
Commonly reported: Nausea (at high doses), Mild GI upset.
Which Manganese (as Manganese Bisglycinate Chelate) supplement scores highest?
Thorne Advanced Nutrients, at 88/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Bone health support
- Antioxidant enzyme cofactor
- Metabolic function
- Connective tissue formation
How it works
- Cofactor for manganese superoxide dismutase (MnSOD)
- Supports collagen cross-linking
- Involved in carbohydrate and lipid metabolism
Dosage
- Typical range
- 1-5 mg daily
- Timing
- With meals
- With food
- Recommended; enhances absorption
- Duration
- Safe for long-term supplementation
- Special populations
- Pregnant/nursing women should not exceed 2 mg/day; kidney disease requires caution
Forms
- Bisglycinate Chelate· 70/100
Safety
Common side effects
- Nausea (at high doses)
- Mild GI upset
Contraindications
- Liver disease
- Biliary obstruction
- Excessive manganese exposure occupationally
Products containing Manganese (as Manganese Bisglycinate Chelate)
Top-scoring supplements in our catalog that list Manganese (as Manganese Bisglycinate Chelate) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Manganese is an established essential mineral with well-defined roles in human physiology. Evidence for bisglycinate chelation improving absorption is good but less robust than for other chelated minerals.
Grade B: Some human trials support key claims; further confirmation needed.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.