Mineral
Manganese (as Manganese Bisglycinate Chelate)
Also known as: Manganese Glycinate, Chelated Manganese, Mn
Manganese is an essential trace mineral involved in bone formation, metabolism, and antioxidant enzyme function (manganese superoxide dismutase). The bisglycinate chelate form is designed for enhanced absorption compared to inorganic salts.
Primary uses
- Bone health support
- Antioxidant enzyme cofactor
- Metabolic function
- Connective tissue formation
How it works
- Cofactor for manganese superoxide dismutase (MnSOD)
- Supports collagen cross-linking
- Involved in carbohydrate and lipid metabolism
Dosage
- Typical range
- 1-5 mg daily
- Timing
- With meals
- With food
- Recommended; enhances absorption
- Duration
- Safe for long-term supplementation
- Special populations
- Pregnant/nursing women should not exceed 2 mg/day; kidney disease requires caution
Forms
- Bisglycinate Chelate· 70/100
Safety
Common side effects
- Nausea (at high doses)
- Mild GI upset
Contraindications
- Liver disease
- Biliary obstruction
- Excessive manganese exposure occupationally
Evidence notes
Manganese is an established essential mineral with well-defined roles in human physiology. Evidence for bisglycinate chelation improving absorption is good but less robust than for other chelated minerals.
Grade B: Some human trials support key claims; further confirmation needed.
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