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Amino Acid

L-Lysine (Antiviral)

Also known as: L-lysine, Lysine monohydrochloride

B
Evidence

Essential amino acid that inhibits herpes virus replication by competing with arginine.

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Daily target & upper limit

1000 mg / day

L-Lysine (Antiviral) has an established daily reference intake. See best forms, label synonyms, upper-limit warnings, and top-scoring supplements:

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Primary uses

  • Herpes prevention
  • Cold sore treatment
  • Shingles support
  • Immune support

How it works

  • Competes with arginine for viral replication
  • Arginine needed for herpes reproduction
  • Supports collagen synthesis
  • May enhance calcium absorption

Dosage

Typical range
1000-3000mg daily for prevention, up to 9g daily during outbreak
Timing
Divided doses, away from meals
With food
Empty stomach if tolerated
Duration
Ongoing for prevention, higher during outbreaks
Special populations
Those with herpes simplex or shingles history

Forms

  • Capsules
  • Tablets
  • Powder
  • Topical

Safety

Common side effects

  • GI upset
  • Diarrhea at high doses

Contraindications

  • Lysinuric protein intolerance

Products containing L-Lysine (Antiviral)

Top-scoring supplements in our catalog that list L-Lysine (Antiviral) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

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Evidence notes

Good evidence for herpes simplex prevention

Grade B: Some human trials support key claims; further confirmation needed.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.