Nootropic
Lemon Balm
Also known as: Melissa, Melissa officinalis
Gentle calming herb improving focus by reducing anxiety. Safe and pleasant-tasting.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Lemon Balm product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Life Extension Enhanced Stress Relief | 91 A | $0.70 |
| 2 | Pure Encapsulations Daily Stress Formula | 86 A- | $1.38 |
| 3 | Pure Encapsulations Memory Pro | 85 A- | $2.23 |
| 4 | Pure Encapsulations Best-Rest Formula | 84 A- | $1.23 |
| 5 | Pure Encapsulations Daily Immune | 83 A- | $1.13 |
| 6 | Garden of Life mykind Organics Sleep Well Rest & Refresh | 83 A- | $0.77 |
| 7 | Nested Naturals LUNA Gentle Sleep Supplement | 82 A- | $0.73 |
| 8 | Pure Encapsulations Muscle Cramp/Tension Formula | 81 A- | $0.65 |
| 9 | Olly Ultra Strength Goodbye Stress Softgels | 81 A- | $0.67 |
| 10 | Olly Ultra Strength Sleep Softgels | 81 A- | $0.67 |
| 11 | Vital Nutrients Sleep Aide | 81 A- | $1.95 |
| 12 | Natural Factors Mind Retreat | 81 A- | $0.50 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Lemon Balm should I take?
The typical range is 300-600 mg Cyracos or equivalent. Safe long-term
When should I take Lemon Balm?
Any time; higher dose evening. Optional.
Which form of Lemon Balm is best?
Cyracos extract — Standardized, studied. Other forms in the catalog: Tea, Tincture.
Is Lemon Balm safe?
Commonly reported: Drowsiness at high doses. Serious warnings: None. Safe
Which Lemon Balm supplement scores highest?
Life Extension Enhanced Stress Relief, at 91/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Calm focus
- Anxiety
- Sleep support
- Cognitive function
How it works
- GABA transaminase inhibition
- Acetylcholine receptor activity
- Mild sedative
Dosage
- Typical range
- 300-600 mg Cyracos or equivalent
- Timing
- Any time; higher dose evening
- With food
- Optional
- Duration
- Safe long-term
- Special populations
- Mild anxiety, sleep support
Forms
- Cyracos extract
- Tea
- Tincture
Safety
Common side effects
- Drowsiness at high doses
Contraindications
- None
Products containing Lemon Balm
Top-scoring supplements in our catalog that list Lemon Balm on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Gentle anxiolytic with cognitive benefits
Grade B: Some human trials support key claims; further confirmation needed.
Related in Nootropic
Check a full stack
Formulate's free interaction checker lets you paste in any combination of supplements and medications at once — every pairing flags severity, timing, and cited evidence.
Open the checkerWhere does Lemon Balm fit in your stack?
Answer two questions and get a stack graded on research — every ingredient scored on the evidence behind it, not the marketing.
Build my stack2 questions · free · no account needed to start
Also on iPhone — get the free app
Evidence-based supplement guides, no spam
We send a short digest when new guides drop — nothing else. No affiliate pushes, no sponsored content, unsubscribe anytime.
Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.