Amino Acid
L-Glutamine
Also known as: Glutamine, Gln, L-Glutamine (Wound Healing)
Most abundant amino acid in the body. Critical for gut lining integrity, immune function, and muscle recovery.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Daily target & upper limit
5 g / dayL-Glutamine has an established daily reference intake. See best forms, label synonyms, upper-limit warnings, and top-scoring supplements:
L-Glutamine dosage reference →Primary uses
- Gut health
- Muscle recovery
- Immune support
- Leaky gut
- Tissue repair
- Gut healing
- Burns
How it works
- Primary fuel for intestinal cells
- Supports gut barrier integrity
- Immune cell fuel
- Muscle protein synthesis
Dosage
- Typical range
- 5-20 g daily in divided doses
- Timing
- Between meals or post-workout
- With food
- Between meals often better
- Duration
- Safe long-term
- Special populations
- Gut issues, athletes, critical illness
Forms
- Powder
- Capsules
Safety
Common side effects
- Well tolerated
Contraindications
- Severe liver disease
- Some cancers (consult oncologist)
Products containing L-Glutamine
Top-scoring supplements in our catalog that list L-Glutamine on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Important for gut and muscle
Grade B: Some human trials support key claims; further confirmation needed.
Cited research for L-Glutamine
Clinical studies referenced across Formulate guides that mention l-glutamine. Each links to the full study page with PubMed source + the guides that cite it.
Related in Amino Acid
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.