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Amino Acid

L-Cystine

Also known as: Cystine, L-Cystine

B
Evidence

Oxidized dimer form of cysteine, important for keratin production, hair/nail/skin health, and antioxidant support via glutathione synthesis.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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The highest-scored L-Cystine product in our catalog (85/100). Track dose and overlaps in the app.
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Every L-Cystine product we have scored

Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.

Common questions

How much L-Cystine should I take?

The typical range is 500-1500 mg daily. Safe long-term

When should I take L-Cystine?

With meals. Best with food.

Which form of L-Cystine is best?

Capsule — Common form. Other forms in the catalog: Powder.

Is L-Cystine safe?

Commonly reported: Well tolerated. Serious warnings: None at normal doses. Caution in cystinuria

Which L-Cystine supplement scores highest?

Thorne Amino Complex - Travel Packs - Berry, at 85/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.

Primary uses

  • Hair health
  • Nail strength
  • Skin support
  • Keratin synthesis
  • Glutathione precursor

How it works

  • Reduced to cysteine in the body
  • Provides sulfur for keratin production
  • Supports glutathione synthesis
  • Structural component of hair and nails

Dosage

Typical range
500-1500 mg daily
Timing
With meals
With food
Best with food
Duration
Safe long-term
Special populations
Hair/nail support

Forms

  • Capsule
  • Powder

Safety

Common side effects

  • Well tolerated

Contraindications

  • Cystinuria

Products containing L-Cystine

Top-scoring supplements in our catalog that list L-Cystine on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

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Evidence notes

Established role in keratin synthesis and sulfur metabolism

Grade B: Some human trials support key claims; further confirmation needed.

Related in Amino Acid

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.