Stack

Hormone Detox Support Stack

Also known as: Estrogen detox stack, Hormone metabolism stack

Evidence

Estrogen metabolism support: DIM, Calcium D-Glucarate, Sulforaphane, NAC.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

Estrogen metabolism
Hormone detoxification
Liver support

How it works

Multi-pathway estrogen metabolism
Phase 1 and 2 support
Elimination support
Antioxidant protection

Dosage

Typical range: DIM 100-200mg + Calcium D-Glucarate 500-1000mg + Sulforaphane 30-60mg + NAC 600mg
Timing: Divided through day
With food: With meals
Duration: Ongoing for hormone metabolism support
Special populations: Estrogen dominance, hormone metabolism support

Forms

Separate supplements

Safety

Common side effects

See individual components

Contraindications

Hormone-sensitive cancers (discuss with oncologist)

Evidence notes

Evidence-based hormone metabolism support

Grade B: Some human trials support key claims; further confirmation needed.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.