Sleep

GABA (Supplemental)

Also known as: GABA (Gamma-Aminobutyric Acid)

Evidence

Inhibitory neurotransmitter supplement with debated BBB penetration. May work peripherally for relaxation.

Primary uses

Relaxation
Sleep support
Stress reduction

How it works

Main inhibitory neurotransmitter
BBB penetration debated
May work via gut-brain axis

Dosage

Typical range: 250-750 mg daily
Timing: Evening
With food: Optional
Duration: Acute effects
Special populations: Mild anxiety, sleep

Forms

Capsules
PharmaGABA

Safety

Common side effects

Drowsiness
Tingling

Contraindications

None

Evidence notes

Debated effectiveness - BBB penetration unclear

Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.