Performance
Arachidonic Acid (ARA)
Also known as: ARA, Arachidonic acid, X-Factor
C
Evidence
Omega-6 fatty acid that amplifies exercise-induced muscle signaling. Increases training response but also inflammation.
Primary uses
- Muscle building
- Training response
- Anabolic signaling
- Strength
How it works
- Prostaglandin precursor
- Amplifies exercise inflammatory response
- Increases muscle protein synthesis signaling
- Works through COX pathway
Dosage
- Typical range
- 250-500mg daily
- Timing
- Pre-workout
- With food
- With fat
- Duration
- Cycle 4-8 weeks on, 4 weeks off
- Special populations
- Advanced trainers, those seeking amplified response
Forms
- Softgel
Safety
Common side effects
- Increased soreness
- Inflammation
Contraindications
- Inflammatory conditions
- Joint issues
- Heart disease
Evidence notes
Mechanism makes sense, limited but positive clinical data
Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.
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