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ginseng and maoi

Ginseng may cause hypertensive crisis with MAOIs

What's happening

Ginseng may have MAO-inhibiting properties. Combined with MAOI antidepressants, can cause dangerous blood pressure elevation, hypertensive crisis, and potentially serotonin syndrome.

Recommendation

Avoid ginseng entirely while on MAOIs.

Timing

Do not combine

Sources

  • Journal of Clinical Psychopharmacology
  • PMID: 3722151

Frequently Asked Questions

Can I take ginseng and maoi together?

Ginseng may cause hypertensive crisis with MAOIs. Avoid ginseng entirely while on MAOIs.

How should I time ginseng and maoi?

Do not combine

Is this interaction dangerous?

This interaction is rated “Danger” by Formulate. Ginseng may have MAO-inhibiting properties. Combined with MAOI antidepressants, can cause dangerous blood pressure elevation, hypertensive crisis, and potentially serotonin syndrome.

Want to check your whole stack?

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Medical disclaimer. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.