Chromium may enhance insulin sensitivity
Chromium picolinate enhances insulin action by improving insulin receptor sensitivity. Combined with insulin, may cause hypoglycemia (low blood sugar). Particularly risky with high-dose chromium (>1000 mcg).
Monitor blood sugar closely. May need insulin dose reduction.
Check blood sugar more frequently when starting chromium
Chromium may enhance insulin sensitivity. Monitor blood sugar closely. May need insulin dose reduction.
Check blood sugar more frequently when starting chromium
This interaction is rated “Warning” by Formulate. Chromium picolinate enhances insulin action by improving insulin receptor sensitivity. Combined with insulin, may cause hypoglycemia (low blood sugar). Particularly risky with high-dose chromium (>1000 mcg).
Studies from our registry that mention chromium or insulin. Each links to the primary source and the other Formulate pages citing it.
Mentions insulin · 2012
Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease
Loguercio C, Andreone P, Brisc C, et al. · Free Radical Biology and Medicine
12-month RCT (n=138) in NAFLD found a silybin-phosphatidylcholine-vitamin E complex reduced insulin resistance and liver enzymes vs placebo, supporting phytosome forms of silymarin for NAFLD.
Mentions insulin · 2011
Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans
Timmers S, Konings E, Bilet L, et al. · Cell Metabolism
30-day crossover RCT in obese men (n=11) found 150mg/day resveratrol improved mitochondrial function, insulin sensitivity, and reduced blood pressure — mimicking several caloric-restriction effects.
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Medical disclaimer. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.
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