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blood thinners and nattokinase

Nattokinase has potent blood-thinning properties

What's happening

Nattokinase is a fibrinolytic enzyme that directly breaks down fibrin and inhibits platelet aggregation. Combined with any anticoagulant (warfarin, aspirin, DOACs), dramatically increases bleeding risk.

Recommendation

Do NOT take nattokinase with any blood thinner. Consult doctor before use.

Timing

Avoid combination entirely; stop 2 weeks before surgery

Sources

  • — Nutrition Research
  • — PMID: 19818632
  • — PMID: 15046501

Frequently Asked Questions

Can I take blood thinners and nattokinase together?

Nattokinase has potent blood-thinning properties. Do NOT take nattokinase with any blood thinner. Consult doctor before use.

How should I time blood thinners and nattokinase?

Avoid combination entirely; stop 2 weeks before surgery

Is this interaction dangerous?

This interaction is rated “Danger” by Formulate. Nattokinase is a fibrinolytic enzyme that directly breaks down fibrin and inhibits platelet aggregation. Combined with any anticoagulant (warfarin, aspirin, DOACs), dramatically increases bleeding risk.

Want to check your whole stack?

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Medical disclaimer. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.