Mineral
Zinc (as Zinc Sulfate)
Also known as: zinc sulfate, zinc sulphate, ZnSO4
Zinc sulfate is an inorganic zinc salt with moderate bioavailability, used in supplements for immune function, wound healing, and protein synthesis. Absorption is better on an empty stomach but may cause nausea.
Primary uses
- immune function
- wound healing
- protein synthesis
- enzyme function
How it works
- cofactor for 100+ enzymes
- supports T-cell and B-cell function
- antioxidant activity
Dosage
- Typical range
- 8–15 mg daily (elemental zinc for adults)
- Timing
- best absorbed on empty stomach, but may take with food if GI upset occurs
- With food
- Food reduces absorption; take 1–2 hours apart from calcium, iron, magnesium
- Duration
- Long-term use >25 mg daily may impair copper absorption; avoid exceeding UL of 40 mg daily
- Special populations
- Pregnant/lactating women: 11–13 mg daily; vegetarians may need higher intake
Forms
- zinc sulfate· 70/100
Safety
Common side effects
- nausea
- metallic taste
- abdominal cramping
Contraindications
- copper deficiency (zinc excess impairs copper absorption)
Evidence notes
Zinc has good evidence for immune support and wound healing; sulfate form has moderate bioavailability compared to glycinate or picolinate.
Grade B: Some human trials support key claims; further confirmation needed.
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