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Mineral

Zinc (as Zinc Sulphate)

Also known as: Zinc sulfate, Zinc sulphate monohydrate, ZnSO₄

A
Evidence

Zinc is an essential trace mineral critical for immune function, protein synthesis, and wound healing. Zinc sulphate is an inorganic salt form with moderate bioavailability.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

  • Immune function support
  • Wound healing
  • Skin health
  • Protein synthesis
  • Enzyme function

How it works

  • Component of immune cell development and function
  • Cofactor for zinc finger proteins and DNA transcription
  • Required for collagen synthesis and wound healing
  • Antioxidant defense via superoxide dismutase
  • Involved in taste and smell perception

Dosage

Typical range
8-11 mg daily (adult women RDA: 8 mg; adult men RDA: 11 mg)
Timing
Can be taken any time; consistent daily timing recommended
With food
Take with food to improve absorption and reduce GI irritation
Duration
Safe for long-term daily use at RDA levels; extended high doses (>40 mg/day) require medical supervision
Special populations
Pregnant women: 11 mg daily; Lactating women: 12 mg daily; Plant-based dieters may need higher intake due to lower bioavailability

Forms

  • Zinc sulphate· 70/100

Safety

Common side effects

  • Nausea (especially on empty stomach)
  • Metallic taste
  • Stomach upset
  • Copper depletion (with chronic high-dose use)

Contraindications

  • Chronic high-dose use without copper supplementation
  • Severe kidney disease (without medical supervision)

Products containing Zinc (as Zinc Sulphate)

Top-scoring supplements in our catalog that list Zinc (as Zinc Sulphate) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

Thorne
Zinc Bisglycinate 30 mg
96
Thorne
Zinc Picolinate 30 mg
96
Thorne
Zinc Bisglycinate 15 mg
91
Nutricost
Calcium + Magnesium + Zinc Citrates with Vitamin D3 Powder
90
See all products →

Evidence notes

Zinc is well-established as essential with strong RCT evidence for immune support and cold duration reduction. Zinc sulphate has moderate bioavailability; chelated or amino acid forms may be better absorbed.

Grade A: Multiple well-designed human trials support the main claims.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.