Hormone Support

Vitex (PMS)

Also known as: Chasteberry, Vitex agnus-castus, Monk's pepper

Evidence

Well-researched herb for PMS symptoms, supporting progesterone and reducing prolactin.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

Find the best Vitex (PMS) supplements — free

See Vitex (PMS) products scored on dose & form, then track your intake in the app.

Open app →

Primary uses

PMS symptoms
Breast tenderness
Cycle regulation
Mood (luteal)

How it works

Supports progesterone in luteal phase
Reduces prolactin
Regulates LH/FSH
Takes 3+ cycles for effect

Dosage

Typical range: 20-40mg standardized extract daily
Timing: Morning, empty stomach
With food: No, empty stomach
Duration: 3-6 months for full effect
Special populations: PMS, luteal phase symptoms, breast tenderness

Forms

Standardized extract
Tincture

Safety

Common side effects

Headache
GI upset
Acne initially
Cycle changes

Contraindications

Pregnancy
Hormone-sensitive cancers
IVF/fertility treatments

Evidence notes

Strong evidence for PMS symptom reduction

Grade A: Multiple well-designed human trials support the main claims.

Related in Hormone Support

Check a full stack

Formulate's free interaction checker lets you paste in any combination of supplements and medications at once — every pairing flags severity, timing, and cited evidence.

Open the checker

Where does Vitex (PMS) fit in your stack?

Answer two questions and get a stack graded on research — every ingredient scored on the evidence behind it, not the marketing.

Build my stack

2 questions · free · no account needed to start

Also on iPhone — get the free app

📬 Get new guides in your inbox

Evidence-based supplement guides, no spam

We send a short digest when new guides drop — nothing else. No affiliate pushes, no sponsored content, unsubscribe anytime.

Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.