Hormone Support

Vitex (PMS)

Also known as: Chasteberry, Vitex agnus-castus, Monk's pepper

Evidence

Well-researched herb for PMS symptoms, supporting progesterone and reducing prolactin.

Primary uses

PMS symptoms
Breast tenderness
Cycle regulation
Mood (luteal)

How it works

Supports progesterone in luteal phase
Reduces prolactin
Regulates LH/FSH
Takes 3+ cycles for effect

Dosage

Typical range: 20-40mg standardized extract daily
Timing: Morning, empty stomach
With food: No, empty stomach
Duration: 3-6 months for full effect
Special populations: PMS, luteal phase symptoms, breast tenderness

Forms

Standardized extract
Tincture

Safety

Common side effects

Headache
GI upset
Acne initially
Cycle changes

Contraindications

Pregnancy
Hormone-sensitive cancers
IVF/fertility treatments

Evidence notes

Strong evidence for PMS symptom reduction

Grade A: Multiple well-designed human trials support the main claims.

Related in Hormone Support

Check a full stack

Formulate's free interaction checker lets you paste in any combination of supplements and medications at once — every pairing flags severity, timing, and cited evidence.

Open the checker

Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.