Herbal Extract
Turmeric Extract (Curcuma longa)
Also known as: Curcumin, Curcuma longa rhizome extract, Turmeric rhizome, Standardized turmeric extract
Turmeric extract is a standardized source of curcumin, a polyphenol compound with demonstrated anti-inflammatory and antioxidant properties supported by substantial clinical research. Multiple RCTs show efficacy for joint comfort, inflammatory markers, and general wellness when combined with bioavailability enhancers like black pepper extract (piperine).
Primary uses
- Joint and inflammatory support
- Antioxidant support
- General anti-inflammatory wellness
- Cognitive and mood support
How it works
- Inhibition of NF-κB signaling pathway
- Suppression of pro-inflammatory cytokines (TNF-α, IL-6, IL-8)
- Free radical scavenging and antioxidant activity
- Modulation of COX-2 and other inflammatory enzymes
Dosage
- Typical range
- 300–2,000 mg daily (standardized to 95% curcuminoids)
- Timing
- With meals
- With food
- Take with fat-containing food and black pepper extract (piperine, 5–10 mg) to enhance bioavailability by up to 2,000%
- Duration
- Safe for long-term use (6+ months in clinical trials); effects may accumulate over 4–8 weeks
- Special populations
- Generally safe in pregnancy at food levels; avoid therapeutic doses if pregnant. Caution in bleeding disorders or prior to surgery.
Forms
- Powder· 70/100
- Capsule· 70/100
- Tablet· 70/100
- Standardized extract (95% curcuminoids typical)· 70/100
Safety
Common side effects
- Mild gastrointestinal upset (nausea, diarrhea) at higher doses
- Bitter taste
- Headache (rare)
- Allergic reactions (very rare)
Contraindications
- Active bleeding or bleeding disorders (may have mild antiplatelet effects)
- Scheduled surgery (discontinue 2 weeks prior)
- Gallbladder obstruction or biliary disorders
- High-dose use in pregnancy (food amounts are safe)
Evidence notes
Good clinical evidence for anti-inflammatory and joint health benefits in multiple RCTs, though bioavailability remains a limitation without absorption enhancers. Extensive mechanistic research supports safety and efficacy. Grade reflects established but somewhat modest effect sizes in some populations.
Grade B: Some human trials support key claims; further confirmation needed.
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