Herbal Extract
Trigonella foenum-graecum Extract (Seed)
Also known as: Fenugreek Extract, Methi Extract, 4-Hydroxyisoleucine Source
A seed extract containing trigonelline and protodioscin with traditional use for hormonal health, lactation support, and blood sugar management. Moderate evidence supports some metabolic applications.
Primary uses
- Blood glucose regulation
- Testosterone and sexual function (claimed)
- Lactation support
- Inflammation reduction
How it works
- 4-Hydroxyisoleucine (soluble fiber component) improves insulin sensitivity
- Trigonelline may have neuroprotective properties
- Protodioscin content provides hormonal support (limited evidence)
Dosage
- Typical range
- 500-1000 mg daily of standardized extract (or 1-5g whole seed)
- Timing
- With meals for blood sugar; flexible for other uses
- With food
- Recommended for GI tolerance and absorption
- Duration
- 4-8 weeks for glycemic effects; lactation benefits within days
- Special populations
- Generally safe in pregnancy for lactation support (consult provider); monitor glucose if diabetic
Forms
- Seed Extract (3% Trigonelline, 1% Protodioscin)· 70/100
Safety
Common side effects
- Maple-like body odor
- Gastrointestinal upset, diarrhea
- Abdominal discomfort
- Allergic reactions (rare; cross-reactivity with peanuts/chickpeas)
Contraindications
- Peanut allergy (potential cross-reactivity)
- Uncontrolled hypoglycemia
- Bleeding disorders (coumarin content)
Evidence notes
Good evidence for blood sugar and lactation support; moderate clinical trial data. Sexual function claims have less robust support. Well-studied for glycemic effects.
Grade B: Some human trials support key claims; further confirmation needed.
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