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Mineral

Selenium (as Fermented Selenium Glycinate)

Also known as: Selenium glycinate, Chelated selenium, Organic selenium

A
Evidence

Selenium is an essential trace mineral incorporated into selenoproteins that provide antioxidant defense and thyroid hormone metabolism. Glycinate chelation may improve absorption compared to inorganic forms.

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Primary uses

  • Antioxidant defense
  • Thyroid hormone metabolism
  • Immune support
  • Reproductive health

How it works

  • Component of glutathione peroxidase and thioredoxin reductase
  • Selenoprotein synthesis
  • Thyroid peroxidase cofactor
  • Free radical neutralization

Dosage

Typical range
50-200 mcg daily
Timing
Consistent daily timing recommended
With food
Can be taken with or without food
Duration
Ongoing supplementation recommended; upper limit generally 400 mcg/day
Special populations
RDA: 55 mcg (adults), 60 mcg (pregnant), 70 mcg (lactating), 20-40 mcg (children). Upper limit: 400 mcg/day to avoid selenosis.

Forms

  • Selenium glycinate (chelated form)· 70/100

Safety

Common side effects

  • Garlic odor on breath
  • Nausea at high doses

Contraindications

  • History of selenosis
  • Excessive iodine intake combined with high selenium (may worsen thyroid dysfunction)

Products containing Selenium (as Fermented Selenium Glycinate)

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Evidence notes

Strong RCT evidence supports selenium's role in antioxidant defense and thyroid health. Organic/chelated forms show improved bioavailability in comparison studies.

Grade A: Multiple well-designed human trials support the main claims.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.