Mineral
Iron (as Ferrous Fumarate)
Also known as: ferrous fumarate, iron(II) fumarate, Fe2+
Ferrous fumarate is a highly bioavailable form of iron used to prevent and treat iron deficiency anemia by supporting oxygen transport and energy metabolism. It is one of the most absorbable iron salts available.
Primary uses
- iron deficiency anemia treatment
- anemia prevention
- oxygen transport
- energy production
How it works
- component of hemoglobin for oxygen transport
- component of myoglobin for muscle oxygen storage
- cofactor in cytochrome P450 enzymes
- supports cellular energy production
Dosage
- Typical range
- 18-27 mg elemental iron daily (adult women); 8-11 mg daily (adult men)
- Timing
- take on empty stomach for optimal absorption, or with small amount of food if GI upset occurs
- With food
- preferably without food, but avoid dairy, calcium, and coffee which reduce absorption
- Duration
- treatment duration depends on deficiency severity; typically several months for repletion
- Special populations
- pregnant women: 27 mg daily; children require age-adjusted dosing; avoid in hereditary hemochromatosis
Forms
- tablet· 70/100
- capsule· 70/100
- liquid· 70/100
Safety
Common side effects
- constipation
- nausea
- abdominal discomfort
- dark stools
- vomiting
Contraindications
- hemochromatosis
- hemosiderosis
- repeated blood transfusions
- active GI bleeding
Evidence notes
Iron deficiency anemia treatment is supported by extensive clinical evidence; ferrous fumarate specifically has strong bioavailability data.
Grade A: Multiple well-designed human trials support the main claims.
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