Adaptogen
Schisandra
Also known as: Five-flavor berry, Schisandra (Schisandra chinensis), Schisandra chinensis, Wu Wei Zi
Five-flavor berry adaptogen. Supports liver, stress resilience, and endurance.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Schisandra product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Natural Factors AdrenaSense | 82 A- | $0.70 |
| 2 | Nature's Way Schisandra Fruit | 78 B+ | $0.29 |
| 3 | Terra Origin Healthy Stress Relief | 78 B+ | $0.67 |
| 4 | Vital Nutrients Schisandra Extract 1000mg | 78 B+ | $0.78 |
| 5 | Natural Factors Liver Health Formula | 78 B+ | $1.00 |
| 6 | Vital Nutrients Liver Support | 77 B+ | $1.13 |
| 7 | Codeage Clearhead Echinacea+ | 76 B+ | $1.10 |
| 8 | NOW Foods Liver Refresh | 76 B+ | $0.50 |
| 9 | Bluebonnet Nutrition THYROID BOOST | 76 B+ | $1.05 |
| 10 | Herb Pharm Schisandra | 76 B+ | $0.40 |
| 11 | Bluebonnet Nutrition JUSTBREATHE | 75 B+ | $1.03 |
| 12 | Zhou Nutrition Thyroid Support | 74 B+ | $0.71 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Schisandra should I take?
The typical range is 500-1000mg extract. Safe long-term
When should I take Schisandra?
Morning or divided. Either.
Which form of Schisandra is best?
Capsule — Extract. Other forms in the catalog: Powder.
Is Schisandra safe?
Commonly reported: GI upset, Decreased appetite. Serious warnings: May affect drug metabolism. Liver protective
Which Schisandra supplement scores highest?
Natural Factors AdrenaSense, at 82/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Stress adaptation
- Liver support
- Endurance
- Mental clarity
How it works
- Contains lignans (schisandrins)
- Liver protective
- Modulates cortisol
Dosage
- Typical range
- 500-1000mg extract
- Timing
- Morning or divided
- With food
- Either
- Duration
- Safe long-term
- Special populations
- Liver support + stress
Forms
- Capsule
- Powder
Safety
Common side effects
- GI upset
- Decreased appetite
Contraindications
- Epilepsy
- Peptic ulcer
Products containing Schisandra
Top-scoring supplements in our catalog that list Schisandra on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Good adaptogenic evidence
Grade B: Some human trials support key claims; further confirmation needed.
Schisandra compared head-to-head
Related in Adaptogen
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.