Probiotic

Saccharomyces boulardii

Also known as: CNCM I-745, Florastor, S. boulardii

Evidence

Beneficial yeast probiotic that's antibiotic-resistant. Excellent for diarrhea, C. diff, and antibiotic support.

Primary uses

Diarrhea
Antibiotic support
C. diff prevention
Traveler's diarrhea

How it works

Not killed by antibiotics
Secretes anti-toxin factors
Supports gut barrier

Dosage

Typical range: 250-500 mg (5-10 billion cells) daily
Timing: During and after antibiotics
With food: Either way
Duration: During infection/antibiotics and 2 weeks after
Special populations: Antibiotic users, recurrent C. diff

Forms

Capsules

Safety

Common side effects

Gas
Bloating

Contraindications

Central venous catheter
Severe immunocompromise

Known interactions

Cautionwith antibiotics
Antibiotics kill probiotic bacteria if taken together

Evidence notes

Strong evidence for diarrhea prevention

Grade A: Multiple well-designed human trials support the main claims.

Related in Probiotic

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.