Probiotic
Bifidobacterium longum
Also known as: B. longum, B. longum 1714, Bifido
Dominant infant gut bacteria that supports immune function and may reduce anxiety. Important throughout life.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Bifidobacterium longum product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Thorne FloraMend Prime Probiotic | 83 A- | $1.87 |
| 2 | Thorne Complete Biotic | 63 B- | $0.83 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Bifidobacterium longum should I take?
The typical range is 1-10 billion CFU daily. Safe long-term
When should I take Bifidobacterium longum?
Any time. Either way.
Which form of Bifidobacterium longum is best?
Capsules — Often in blends.
Is Bifidobacterium longum safe?
Commonly reported: Minimal. Serious warnings: Standard cautions. Safe
Which Bifidobacterium longum supplement scores highest?
Thorne FloraMend Prime Probiotic, at 83/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Immune support
- Anxiety/mood
- Gut health
- Inflammation
What systematic reviews concluded
Outcomes that systematic reviews of Bifidobacterium longum reached a verdict on: 2 with a benefit, 5 unclear. Each is quoted from a review and linked to it on PubMed. How these were read.
Reviews found a benefit (2)
“Probiotic/synbiotic interventions led to significant reductions in CRP (SMD = -0.54), IL-6 (SMD = -0.41), and TNF-α (SMD = -0.48), along with an increase in IL-10 (SMD = +0.38).” PMID 41059033
“Adding probiotics to standard H. pylori therapy not only increased the rate of eradication but also reduced some of the adverse reactions throughout therapy, particularly nausea, vomiting, diarrhea, abdominal pain, epigastric pain/bloating, and taste issues.” PMID 39642994
Not enough to say: quality of life, depression, and anxiety in ibs; bone metabolism (rankl); neurodegenerative disease symptoms; ventilator-associated pneumonia incidence; crohn's disease remission.
5 findings from reviews in specific patient groups (such as cancer, pregnancy or surgery) are not shown here.
How it works
- Immune modulation
- GABA production
- Anti-inflammatory
Dosage
- Typical range
- 1-10 billion CFU daily
- Timing
- Any time
- With food
- Either way
- Duration
- Safe long-term
- Special populations
- Stress, immune support
Forms
- Capsules
Safety
Common side effects
- Minimal
Contraindications
- Severe immunocompromise
Products containing Bifidobacterium longum
Top-scoring supplements in our catalog that list Bifidobacterium longum on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
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Evidence notes
Important from infancy through aging
Grade B: Some human trials support key claims; further confirmation needed.
Cited research for Bifidobacterium longum
Clinical studies referenced across Formulate guides that mention bifidobacterium longum. Each links to the full study page with PubMed source + the guides that cite it.
Related in Probiotic
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.