Probiotic

Lactobacillus plantarum

Also known as: L. plantarum, L. plantarum 299v, LP299v

Evidence

Versatile probiotic with gut barrier support and anti-inflammatory effects. Found in fermented vegetables.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

Gut barrier
IBS support
Inflammation
Gut health

How it works

Strengthens tight junctions
Anti-inflammatory cytokine production
Survives stomach acid well

Dosage

Typical range: 5-20 billion CFU daily
Timing: Any time
With food: Either way
Duration: Safe long-term
Special populations: IBS, leaky gut concerns

Forms

Capsules
Foods

Safety

Common side effects

Minimal

Contraindications

Severe immunocompromise

Products containing Lactobacillus plantarum

Top-scoring supplements in our catalog that list Lactobacillus plantarum on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

Thorne

Women's Daily Probiotic

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Evidence notes

Strong gut barrier support

Grade B: Some human trials support key claims; further confirmation needed.

Cited research for Lactobacillus plantarum

Clinical studies referenced across Formulate guides that mention lactobacillus plantarum. Each links to the full study page with PubMed source + the guides that cite it.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.