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Herbal Extract

Sabroxy (Oroxylum indicum) Extract

Also known as: Oroxylum indicum bark extract, Oroxylin A extract, Shyonaka, Sabroxy®

D
Evidence

Sabroxy is a standardized extract from Oroxylum indicum bark containing oroxylin A, a flavonoid compound studied for potential neuroprotective and cognitive effects. Research is limited primarily to in vitro and animal models, with minimal human clinical data available.

Primary uses

  • Cognitive support
  • Neuroprotection
  • Brain health
  • Antioxidant support

How it works

  • GABA receptor modulation (proposed)
  • Antioxidant activity via oroxylin A
  • Neuroprotective signaling pathways
  • Anti-inflammatory mechanisms

Dosage

Typical range
300-600 mg daily (based on traditional use and early studies)
Timing
Typically morning or divided doses
With food
No specific requirement; may be taken with or without food
Duration
Optimal duration of use not established; human studies lacking
Special populations
Safety in pregnant women, nursing mothers, and children not established; use with caution

Forms

  • Powder extract (10% oroxylin A standardization)· 70/100

Safety

Common side effects

  • Generally well-tolerated in limited human exposure
  • Potential headache or GI upset (anecdotal)
  • Insufficient data for comprehensive side effect profile

Contraindications

  • Pregnancy and breastfeeding (insufficient safety data)
  • Known hypersensitivity to Acanthaceae family plants

Evidence notes

Evidence is primarily limited to in vitro studies and animal models. Oroxylin A shows promise in preclinical research but lacks adequate human clinical trials to establish efficacy or optimal dosing. No robust RCT data in human subjects currently available.

Grade D: Primarily pre-clinical or anecdotal; human efficacy not established.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.