Herbal Extract
Sabroxy (Oroxylum indicum) Extract
Also known as: Oroxylum indicum bark extract, Oroxylin A extract, Shyonaka, Sabroxy®
Sabroxy is a standardized extract from Oroxylum indicum bark containing oroxylin A, a flavonoid compound studied for potential neuroprotective and cognitive effects. Research is limited primarily to in vitro and animal models, with minimal human clinical data available.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Primary uses
- Cognitive support
- Neuroprotection
- Brain health
- Antioxidant support
How it works
- GABA receptor modulation (proposed)
- Antioxidant activity via oroxylin A
- Neuroprotective signaling pathways
- Anti-inflammatory mechanisms
Dosage
- Typical range
- 300-600 mg daily (based on traditional use and early studies)
- Timing
- Typically morning or divided doses
- With food
- No specific requirement; may be taken with or without food
- Duration
- Optimal duration of use not established; human studies lacking
- Special populations
- Safety in pregnant women, nursing mothers, and children not established; use with caution
Forms
- Powder extract (10% oroxylin A standardization)· 70/100
Safety
Common side effects
- Generally well-tolerated in limited human exposure
- Potential headache or GI upset (anecdotal)
- Insufficient data for comprehensive side effect profile
Contraindications
- Pregnancy and breastfeeding (insufficient safety data)
- Known hypersensitivity to Acanthaceae family plants
Products containing Sabroxy (Oroxylum indicum) Extract
Top-scoring supplements in our catalog that list Sabroxy (Oroxylum indicum) Extract on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
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Evidence notes
Evidence is primarily limited to in vitro studies and animal models. Oroxylin A shows promise in preclinical research but lacks adequate human clinical trials to establish efficacy or optimal dosing. No robust RCT data in human subjects currently available.
Grade D: Primarily pre-clinical or anecdotal; human efficacy not established.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.