Antioxidant
Pycnogenol (Prelox for ED)
Also known as: Pine bark extract, French maritime pine, Prelox component
Pine bark extract that with L-Arginine (Prelox) has evidence for erectile dysfunction.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Pycnogenol (Prelox for ED) product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Life Extension Pycnogenol French Maritime Pine Bark Extract | 92 A | $1.10 |
| 2 | Thorne Meta-Balance™ | 90 A | $1.60 |
| 3 | Pure Encapsulations Pycnogenol (pine bark extract) 50 mg | 86 A- | $1.42 |
| 4 | Pure Encapsulations Pycnogenol 100 mg | 86 A- | $2.73 |
| 5 | Bluebonnet Nutrition PYCNOGENOL 50 mg | 84 A- | $1.33 |
| 6 | Healthy Origins Pycnogenol 150mg | 82 A- | $1.04 |
| 7 | NOW Foods Pine Bark Extract | 81 A- | $0.22 |
| 8 | Bluebonnet Nutrition SUPER ANTIOXIDANT FORMULA | 77 B+ | $2.29 |
| 9 | Healthy Origins Pycnogenol 100mg | 76 B+ | $0.83 |
| 10 | Country Life Resveratrol Plus | 61 B- | $0.41 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Pycnogenol (Prelox for ED) should I take?
The typical range is 40-120mg Pycnogenol + 1.7g L-Arginine (Prelox dosing). 1-3 months for ED improvement
When should I take Pycnogenol (Prelox for ED)?
Divided doses. Either way.
Which form of Pycnogenol (Prelox for ED) is best?
Pycnogenol extract — Standardized. Other forms in the catalog: Prelox formula.
Is Pycnogenol (Prelox for ED) safe?
Commonly reported: GI upset, Dizziness, Headache. Serious warnings: May enhance blood thinners. Safe
Which Pycnogenol (Prelox for ED) supplement scores highest?
Life Extension Pycnogenol French Maritime Pine Bark Extract, at 92/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Erectile dysfunction
- Endothelial function
- Blood flow
- Antioxidant
How it works
- Enhances nitric oxide production
- Antioxidant for endothelium
- Prelox formula studied for ED
- Supports blood vessel health
Dosage
- Typical range
- 40-120mg Pycnogenol + 1.7g L-Arginine (Prelox dosing)
- Timing
- Divided doses
- With food
- Either way
- Duration
- 1-3 months for ED improvement
- Special populations
- Mild-moderate ED, endothelial dysfunction
Forms
- Pycnogenol extract
- Prelox formula
Safety
Common side effects
- GI upset
- Dizziness
- Headache
Contraindications
- Autoimmune conditions (immunomodulating)
Products containing Pycnogenol (Prelox for ED)
Top-scoring supplements in our catalog that list Pycnogenol (Prelox for ED) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Good evidence when combined with L-Arginine (Prelox)
Grade B: Some human trials support key claims; further confirmation needed.
Related in Antioxidant
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.