Nootropic
Pramiracetam
Also known as: Diisopropyl-2-oxopyrrolidine-N-acetamide
Most potent racetam for raw memory enhancement. Highly fat-soluble with focused cognitive effects.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Primary uses
- Memory formation
- Focus
- Learning
- High-potency nootropic
How it works
- High-affinity choline uptake
- Enhances memory formation
- Emotionally neutral effects
Dosage
- Typical range
- 300-600 mg daily divided
- Timing
- With fat-containing meals
- With food
- Yes, essential
- Duration
- 2+ weeks for effects
- Special populations
- Memory-focused goals
Forms
- Capsules
- Powder
Safety
Common side effects
- Headache
- GI upset
Contraindications
- None
Evidence notes
Strongest memory-focused racetam
Grade B: Some human trials support key claims; further confirmation needed.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.