Nootropic

Nefiracetam

Also known as: DM-9384

Evidence

Fat-soluble racetam with unique GABAergic effects. Enhances long-term potentiation.

Primary uses

Memory
Mood
Neuroprotection
Apathy

How it works

Enhances GABAergic signaling
Calcium channel modulation
Long-term potentiation enhancement

Dosage

Typical range: 400-800 mg daily divided
Timing: With fatty meals
With food: Yes, essential
Duration: Cumulative benefits
Special populations: Memory, apathy

Forms

Capsules
Powder

Safety

Common side effects

Headache
GI upset

Contraindications

Unknown

Evidence notes

Unique GABAergic racetam

Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.