Nootropic

Phenylethylamine (PEA)

Also known as: PEA, β-Phenylethylamine, Phenylethylamine HCl, 2-phenylethylamine

Evidence

Phenylethylamine (PEA) is an endogenous trace amine that acts as a neuromodulator, primarily known for mood and focus support. Limited human clinical evidence exists; most data is from animal studies or in vitro research.

Primary uses

Mood
Focus
Energy
Rapid onset
Mood elevation
Mental focus and alertness
Energy support

How it works

Releases dopamine and norepinephrine
Trace amine receptor activity
Very rapid metabolism

Dosage

Typical range: 100-500 mg
Timing: As needed, short duration
With food: Empty stomach
Duration: Only lasts 15-30 minutes alone
Special populations: Acute mood boost

Forms

Capsules
Powder
HCl powder· 70/100

Safety

Common side effects

Rapid heart rate
Anxiety
Crash

Contraindications

MAOIs
Heart conditions

Evidence notes

Very short-acting mood boost

Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.