Berberine
Scored by the Formulate Research Team · Last reviewed July 2026
Overview: Thorne Berberine
A powerful botanical for heart health, metabolic support, glucose balance, and GI support* Berberine provides nutritional support for maintaining healthy cholesterol and blood sugar levels, promoting GI microbial balance, and supporting healthy metabolism.*
Score Breakdown
Formulate scores every product across six weighted dimensions. Each dimension is graded independently — hover or tap to see what drove each component.
Ingredients per Serving
| Ingredient | Amount |
|---|---|
| Berberine Phytosome (Berberis aristata extract (root) / Phospholipid complex from Pea, Sunflower, Grape Seed)16 systematic reviews · 54 randomised trials | 1100 mg |
| Berberine HCl (from Indian Barberry extract) (root) (Berberis aristata)16 systematic reviews · 54 randomised trials | 900 mg |
Certifications & Testing
Other Ingredients
Calcium Laurate, Hypromellose (derived from cellulose) capsule
Recommended Use
Take 1-2 capsules two times daily with food or as recommended by your health-care practitioner.
Warnings
ALLERGY WARNING: This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. PREGNANCY WARNING: If pregnant, nursing, or trying to conceive, do not use this product. INTERACTIONS: Has been shown to decrease the activity of the cytochrome p450 (CYP) enzymes CYP2D6, CYP2C9, and CYP3A4. Individuals with a known, serious allergy to peanuts may occasio
Frequently Asked Questions
What is Thorne Berberine's Formulate score?
Thorne Berberine scores 96 out of 100 (grade A) on Formulate's ingredient-level rubric, which weighs evidence quality, dose accuracy, bioavailability, transparency, safety, and manufacturing practices.
Is Thorne Berberine worth it?
Thorne Berberine scores 96/100 (grade A). That puts it in Formulate's top tier: its ingredient doses, forms, and label transparency hold up against the clinical evidence, and it carries credible third-party testing. Formulate grades every product with the same automated rubric, so the score reflects the formula — not marketing or sponsorships.
What's in Thorne Berberine?
Each serving contains Berberine Phytosome (Berberis aristata extract (root) / Phospholipid complex from Pea, Sunflower, Grape Seed) (1100 mg), Berberine HCl (from Indian Barberry extract) (root) (Berberis aristata) (900 mg). Serving size: Two Capsules. 30 servings per container.
How do I take berberine?
Take 1-2 capsules two times daily with food or as recommended by your health-care practitioner.
Who makes Berberine?
Berberine is made by Thorne. See Formulate's full grade and product lineup for Thorne on its brand page.
Is Thorne Berberine third-party tested?
Thorne lists the following certifications and testing for this product: Gluten Free, Soy Free, Dairy Free, Derived From Natural Flavors, Derived From Natural Colors, Thorne Verified, GMP, Manufactured in the USA.
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Disclosure. Formulate may earn a commission from purchases made through links on this page. Commissions never influence scores — every product is graded by the same automated rubric. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.