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Thorne Berberine

Berberine

98A
Grade A · capsule · 30 servings · $44.00

Scored by the Formulate Research Team · Last reviewed May 2026

MetabolismHeart HealthWeight Management

Overview: Thorne Berberine

A powerful botanical for heart health, metabolic support, glucose balance, and GI support* Berberine provides nutritional support for maintaining healthy cholesterol and blood sugar levels, promoting GI microbial balance, and supporting healthy metabolism.*

Score Breakdown

Formulate scores every product across six weighted dimensions. Each dimension is graded independently — hover or tap to see what drove each component.

Evidence Qualityweight 30%
100/ 100
Dose Adequacyweight 25%
99/ 100
Form/Bioavailabilityweight 15%
92/ 100
Transparencyweight 15%
100/ 100
Safety/Redundancyweight 10%
100/ 100
Manufacturing Qualityweight 5%
90/ 100

Ingredients per Serving

IngredientAmount
Berberine Phytosome (Berberis aristata extract (root) / Phospholipid complex from Pea, Sunflower, Grape Seed)1100 mg
Berberine HCl (from Indian Barberry extract) (root) (Berberis aristata)900 mg

Certifications & Testing

Gluten FreeSoy FreeDairy FreeDerived From Natural FlavorsDerived From Natural ColorsThorne VerifiedGMPManufactured in the USA

Other Ingredients

Calcium Laurate, Hypromellose (derived from cellulose) capsule

Recommended Use

Take 1-2 capsules two times daily with food or as recommended by your health-care practitioner.

Warnings

ALLERGY WARNING: This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. PREGNANCY WARNING: If pregnant, nursing, or trying to conceive, do not use this product. INTERACTIONS: Has been shown to decrease the activity of the cytochrome p450 (CYP) enzymes CYP2D6, CYP2C9, and CYP3A4. Individuals with a known, serious allergy to peanuts may occasio

Frequently Asked Questions

What is Thorne Berberine's Formulate score?

Thorne Berberine scores 98 out of 100 (grade A) on Formulate's ingredient-level rubric, which weighs evidence quality, dose accuracy, bioavailability, transparency, safety, and manufacturing practices.

Is Thorne Berberine worth it?

Thorne Berberine scores 98/100 (grade A). That puts it in Formulate's top tier: its ingredient doses, forms, and label transparency hold up against the clinical evidence, and it carries credible third-party testing. Formulate grades every product with the same automated rubric, so the score reflects the formula — not marketing or sponsorships.

What's in Thorne Berberine?

Each serving contains Berberine Phytosome (Berberis aristata extract (root) / Phospholipid complex from Pea, Sunflower, Grape Seed) (1100 mg), Berberine HCl (from Indian Barberry extract) (root) (Berberis aristata) (900 mg). Serving size: Two Capsules. 30 servings per container.

How do I take berberine?

Take 1-2 capsules two times daily with food or as recommended by your health-care practitioner.

Who makes Berberine?

Berberine is made by Thorne. See Formulate's full grade and product lineup for Thorne on its brand page.

Is Thorne Berberine third-party tested?

Thorne lists the following certifications and testing for this product: Gluten Free, Soy Free, Dairy Free, Derived From Natural Flavors, Derived From Natural Colors, Thorne Verified, GMP, Manufactured in the USA.

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Disclosure. Formulate may earn a commission from purchases made through links on this page. Commissions never influence scores — every product is graded by the same automated rubric. This page is for educational purposes only and does not replace advice from a qualified healthcare provider.