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Adaptogen

NooGandha® Ashwagandha Root and Leaf Extract (3.5% Withanolides)

Also known as: Withania somnifera extract, Ashwagandha standardized extract, NooGandha, Indian ginseng extract

B
Evidence

NooGandha is a standardized ashwagandha extract containing at least 3.5% withanolides, the bioactive compounds responsible for the herb's stress-reducing and cognitive effects. Multiple clinical trials support its use for stress management, cortisol modulation, and mood support.

Primary uses

  • Stress and anxiety management
  • Cortisol regulation
  • Sleep quality improvement
  • Mood support
  • Cognitive function
  • Physical performance and recovery

How it works

  • Withanolides modulate GABA and serotonin signaling pathways
  • Reduces cortisol levels and HPA-axis activity
  • Antioxidant and anti-inflammatory effects
  • Promotes relaxation without sedation

Dosage

Typical range
250-600 mg daily
Timing
Divided doses with meals; evening dose may support sleep
With food
Recommended with food to enhance absorption and minimize GI upset
Duration
Typical clinical trials used 8-12 weeks; benefits may continue with consistent use
Special populations
Pregnant/nursing women should avoid; use cautiously with autoimmune conditions; may cause drowsiness in sensitive individuals

Forms

  • Capsule· 70/100
  • Extract powder· 70/100
  • Tablet· 70/100

Safety

Common side effects

  • Drowsiness or sedation
  • Mild gastrointestinal upset
  • Headache (rare)
  • Dizziness (rare)

Contraindications

  • Pregnancy and lactation
  • Autoimmune diseases (may overstimulate immune response)
  • Acute illness or high fever
  • Concurrent use with sedative medications requires medical supervision

Evidence notes

Ashwagandha has substantial clinical evidence from multiple RCTs showing efficacy for stress, anxiety, and sleep. The 3.5% withanolide standardization ensures consistent bioactive content. Evidence is strong for stress/anxiety outcomes; moderate for cognitive enhancement.

Grade B: Some human trials support key claims; further confirmation needed.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.