Herbal Extract
Muira Puama Extract
Also known as: Ptychopetalum olacoides, Potency wood, Marapuama, Muira puama bark
Muira puama is a traditional Amazonian plant historically used for sexual function and vitality, though clinical evidence in humans remains limited and mostly preliminary. Most research consists of small or animal studies, with few rigorous controlled trials in humans.
Primary uses
- Sexual function and libido
- Erectile dysfunction
- General vitality and energy
How it works
- Potential vasodilation via increased nitric oxide
- Possible neurotransmitter modulation
- Traditional use suggests adaptogenic properties
Dosage
- Typical range
- 1,000–2,000 mg daily (standardized extract or powder)
- Timing
- Can be taken with or without meals; often split into divided doses
- With food
- No specific requirement; may be taken with or without food
- Duration
- Traditional use suggests 4–12 weeks for potential effects; limited data on long-term safety
- Special populations
- Avoid during pregnancy/lactation; limited safety data in children
Forms
- Powder extract· 70/100
- Capsule· 70/100
- Liquid extract· 70/100
Safety
Common side effects
- Generally well-tolerated
- Rare reports of insomnia or nervousness at high doses
- Mild gastrointestinal upset possible
Contraindications
- Pregnancy and lactation (insufficient safety data)
- Hormone-sensitive conditions (theoretical concern; limited evidence)
- Cardiovascular disease (use with caution; no direct contraindication but limited safety data)
Evidence notes
Limited human clinical trials; most evidence from traditional use, animal studies, or very small uncontrolled human studies. A few small RCTs show modest benefits for sexual function, but sample sizes are typically <100 subjects and methodological rigor is variable. Insufficient evidence for strong recommendation.
Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.
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