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Mushroom

Maitake (Grifola frondosa)

Also known as: Hen of the woods, Grifola frondosa, Dancing mushroom

B
Evidence

Culinary and medicinal mushroom with D-fraction compound studied for immune enhancement and blood sugar support.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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The highest-scored Maitake (Grifola frondosa) product in our catalog (83/100). Track dose and overlaps in the app.
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Every Maitake (Grifola frondosa) product we have scored

Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.

Common questions

How much Maitake (Grifola frondosa) should I take?

The typical range is 500-1500mg extract or 3-7g whole mushroom daily. Long-term use appropriate

When should I take Maitake (Grifola frondosa)?

With meals for blood sugar. Either way for immunity.

Which form of Maitake (Grifola frondosa) is best?

D-fraction extract — Most studied for immunity. Other forms in the catalog: Whole mushroom powder, Hot water extract, Fresh/culinary.

Is Maitake (Grifola frondosa) safe?

Commonly reported: Rare, well tolerated. Serious warnings: May lower blood sugar significantly. Safe

Which Maitake (Grifola frondosa) supplement scores highest?

Pure Encapsulations Daily Immune, at 83/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.

Primary uses

  • Immune support
  • Blood sugar
  • Cancer adjunct
  • Metabolic health

How it works

  • D-fraction is potent immunomodulator
  • Enhances macrophage and NK cell activity
  • May improve insulin sensitivity
  • Supports healthy blood sugar

Dosage

Typical range
500-1500mg extract or 3-7g whole mushroom daily
Timing
With meals for blood sugar
With food
Either way for immunity
Duration
Long-term use appropriate
Special populations
Those with metabolic concerns, immune support

Forms

  • D-fraction extract
  • Whole mushroom powder
  • Hot water extract
  • Fresh/culinary

Safety

Common side effects

  • Rare, well tolerated

Contraindications

  • Hypoglycemia
  • Bleeding disorders

Products containing Maitake (Grifola frondosa)

Top-scoring supplements in our catalog that list Maitake (Grifola frondosa) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

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Evidence notes

Good research especially for D-fraction extract

Grade B: Some human trials support key claims; further confirmation needed.

Related in Mushroom

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.