Botanical
Licorice Root (Glycyrrhiza glabra)
Also known as: Glycyrrhiza glabra, DGL (deglycyrrhizinated), Licorice extract
Traditional antiviral herb with glycyrrhizin compound showing activity against multiple viruses.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Licorice Root (Glycyrrhiza glabra) product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Complement Gut Nurture | 89 A | $1.93 |
| 2 | Thorne GI Relief | 88 A | $0.46 |
| 3 | Nutricost Licorice Root Capsules | 87 A | $0.12 |
| 4 | Thorne Stress Balance | 85 A- | $0.77 |
| 5 | Pure Encapsulations Epi-Integrity powder | 85 A- | $2.00 |
| 6 | Vital Nutrients DGL Powder | 85 A- | $0.09 |
| 7 | Pure Encapsulations DGL Plus | 83 A- | $0.44 |
| 8 | Pure Encapsulations PhytoBalance II | 82 A- | $0.47 |
| 9 | Pure Encapsulations ADR Formula | 82 A- | $0.77 |
| 10 | Vital Nutrients Licorice Root Extract 400mg | 81 A- | $0.32 |
| 11 | Nature's Way Licorice Root | 80 A- | $0.29 |
| 12 | Terra Origin Healthy Gut Reset PM | 79 B+ | $0.83 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Licorice Root (Glycyrrhiza glabra) should I take?
The typical range is 200-400mg standardized extract (non-DGL) for short periods. Short-term only (2-4 weeks) for whole extract
When should I take Licorice Root (Glycyrrhiza glabra)?
With meals. Yes.
Which form of Licorice Root (Glycyrrhiza glabra) is best?
Whole root extract — Contains glycyrrhizin (monitor BP). Other forms in the catalog: DGL, Tea/decoction.
Is Licorice Root (Glycyrrhiza glabra) safe?
Commonly reported: Edema, Headache, Fatigue, Elevated blood pressure. Serious warnings: Raises blood pressure and causes potassium loss, Hypokalemia risk, Pseudoaldosteronism. Avoid with liver or kidney disease
Which Licorice Root (Glycyrrhiza glabra) supplement scores highest?
Complement Gut Nurture, at 89/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Antiviral
- Adrenal support
- Sore throat
- Digestive support
How it works
- Glycyrrhizin has antiviral activity
- Supports adrenal function
- Soothes mucous membranes
- Anti-inflammatory effects
Dosage
- Typical range
- 200-400mg standardized extract (non-DGL) for short periods
- Timing
- With meals
- With food
- Yes
- Duration
- Short-term only (2-4 weeks) for whole extract
- Special populations
- Those with viral infections, adrenal fatigue
Forms
- Whole root extract
- DGL
- Tea/decoction
Safety
Common side effects
- Edema
- Headache
- Fatigue
- Elevated blood pressure
Contraindications
- Hypertension
- Heart disease
- Kidney disease
- Hypokalemia
- Pregnancy
Products containing Licorice Root (Glycyrrhiza glabra)
Top-scoring supplements in our catalog that list Licorice Root (Glycyrrhiza glabra) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Traditional use with in vitro antiviral evidence
Grade B: Some human trials support key claims; further confirmation needed.
Related in Botanical
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.