Amino Acid
L-Citrulline
Also known as: Citrulline, Citrulline malate
B
Evidence
More effective nitric oxide booster than arginine. Converts to arginine while bypassing liver metabolism.
Primary uses
- Blood flow
- Exercise performance
- Cardiovascular health
- Pump
How it works
- Converts to arginine in kidneys
- Bypasses hepatic metabolism
- More sustained NO production
Dosage
- Typical range
- 3-6 g citrulline or 6-8 g citrulline malate
- Timing
- 30-60 min before exercise
- With food
- Optional
- Duration
- Safe long-term
- Special populations
- Athletes, blood flow support
Forms
- Powder
- Citrulline malate
Safety
Common side effects
- Well tolerated
Contraindications
- None
Evidence notes
Superior to arginine for NO production
Grade B: Some human trials support key claims; further confirmation needed.
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