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Fatty Acid

Krill Oil (NKO®)

Also known as: Euphausia superba, Antarctic krill oil, NKO™

B
Evidence

Krill oil is a marine source of omega-3 fatty acids (EPA and DHA) bound to phospholipids, which may enhance bioavailability compared to fish oil triglycerides. NKO® is a patented, sustainably harvested krill oil extract standardized for phospholipid content.

Primary uses

  • Cardiovascular health support
  • Cognitive function
  • Joint health
  • Inflammatory response modulation

How it works

  • EPA/DHA omega-3 fatty acids reduce inflammatory mediators
  • Phospholipid form enhances cellular membrane incorporation
  • Astaxanthin provides antioxidant protection

Dosage

Typical range
1,000–3,000 mg daily
Timing
With meals
With food
Recommended; fat-soluble and better absorbed with dietary fat
Duration
Consistent daily use recommended; benefits typically observed after 4–12 weeks
Special populations
Pregnant/nursing women should consult provider; those on anticoagulants should discuss with healthcare provider

Forms

  • Softgel capsules· 70/100

Safety

Common side effects

  • Mild fishy aftertaste
  • Gastrointestinal upset (rare)
  • Nausea (uncommon)

Contraindications

  • Shellfish allergy (krill is a crustacean)
  • Bleeding disorders without medical supervision
  • High-dose anticoagulant therapy without medical consultation

Evidence notes

Multiple RCTs support omega-3 benefits for cardiovascular and cognitive health. Krill oil specifically shows good evidence for lipid profiles and joint comfort. Phospholipid delivery form has emerging evidence for superior absorption vs. triglyceride fish oil.

Grade B: Some human trials support key claims; further confirmation needed.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider.