Fatty Acid
GLA (Evening Primrose Oil)
Also known as: Evening primrose oil, EPO, Gamma-linolenic acid
B
Evidence
Gamma-linolenic acid omega-6 for skin health, PMS, and inflammation. Anti-inflammatory despite being omega-6.
Primary uses
- Skin health
- PMS symptoms
- Inflammation
- Hormone balance
How it works
- GLA converts to anti-inflammatory DGLA
- Supports skin barrier
- May help PMS symptoms
Dosage
- Typical range
- 500-3000 mg EPO daily (providing 40-300mg GLA)
- Timing
- With meals
- With food
- Yes
- Duration
- Benefits develop over weeks
- Special populations
- PMS, eczema, skin concerns
Forms
- Softgel
- Oil
Safety
Common side effects
- GI upset
- Headache
Contraindications
- Seizure disorders
- Before surgery
Evidence notes
Anti-inflammatory omega-6
Grade B: Some human trials support key claims; further confirmation needed.
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