Fatty Acid
LA (Linoleic Acid)
Also known as: Linoleic acid, LA, Omega-6 LA, C18:2
An essential omega-6 fatty acid required for cell membrane structure and skin barrier function. Must be obtained from diet as the body cannot synthesize it.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Primary uses
- Essential fatty acid provision
- Skin barrier function
- Cell membrane integrity
- Precursor to other fatty acids
How it works
- Essential component of cell membranes
- Converts to gamma-linolenic acid (GLA)
- Supports skin barrier ceramide production
- Precursor to arachidonic acid
Dosage
- Typical range
- 11-17 g daily from diet
- Timing
- Throughout day in foods
- With food
- N/A - food source
- Duration
- Essential - ongoing need
- Special populations
- Deficiency rare in Western diets
Forms
- Vegetable oils
- Safflower oil
- Supplements rare
Safety
Common side effects
- None at normal intake
Contraindications
- None
Evidence notes
Essential fatty acid with established physiological roles
Grade B: Some human trials support key claims; further confirmation needed.
Related in Fatty Acid
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.