Herbal Extract
Supercritical CO2 Ginger Extract (Zingiber officinale)
Also known as: ginger root extract, zingiber officinale supercritical extract, ginger CO2 extract, standardized ginger extract
Supercritical CO2 ginger extract is a concentrated form of ginger root standardized to gingerols and shogaols, the primary bioactive compounds responsible for ginger's anti-inflammatory and digestive properties. Extensive research supports ginger's efficacy for nausea, digestive discomfort, and inflammatory responses.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Supercritical CO2 Ginger Extract (Zingiber officinale) product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Pure Encapsulations MotilPro | 90 A | $1.10 |
| 2 | NutraBio Curcumin Advanced | 90 A | $1.23 |
| 3 | Sports Research Elderberry With Vitamin C Capsules, Ginger, Zinc & D3 | 88 A | $0.80 |
| 4 | Nutricost Ginger Root Extract Capsules | 87 A | $0.08 |
| 5 | NOW Foods Ginger Root Extract | 87 A | $0.09 |
| 6 | Pure Encapsulations A.I. Formula | 85 A- | $0.61 |
| 7 | Pure Encapsulations Th1 Support | 83 A- | $1.02 |
| 8 | NutraBio Immune | 83 A- | $1.33 |
| 9 | Bluebonnet Nutrition GINGER ROOT EXTRACT | 80 A- | $0.34 |
| 10 | Viva Naturals Elderberry, Vitamin C + Zinc | 80 A- | $0.42 |
| 11 | Pure Encapsulations UltraNutrient | 77 B+ | $1.92 |
| 12 | Terra Origin Organic Turmeric Blend | 77 B+ | $0.67 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Supercritical CO2 Ginger Extract (Zingiber officinale) should I take?
The typical range is 1–2 grams daily (extract equivalent; adjust based on gingerol content standardization). Safe for long-term use; many studies show efficacy with 4–12 weeks of consistent supplementation
When should I take Supercritical CO2 Ginger Extract (Zingiber officinale)?
With meals for digestive support; 30–60 minutes before travel for nausea. Recommended with food to minimize potential gastric irritation.
Which form of Supercritical CO2 Ginger Extract (Zingiber officinale) is best?
Capsule. Other forms in the catalog: Powder, Extract.
Is Supercritical CO2 Ginger Extract (Zingiber officinale) safe?
Commonly reported: Mild gastrointestinal upset at higher doses, Heartburn or acid reflux (occasional), Mouth irritation with powdered forms.
Which Supercritical CO2 Ginger Extract (Zingiber officinale) supplement scores highest?
Pure Encapsulations MotilPro, at 90/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Nausea and motion sickness
- Digestive support
- Anti-inflammatory effects
- Joint comfort
- Gastrointestinal health
How it works
- Gingerols and shogaols inhibit inflammatory mediators (TNF-α, IL-6, NF-κB pathway)
- 5-HT antagonism and antiemetic effects via vagal afferent signaling
- Promotes gastric motility and digestive enzyme activity
- Antioxidant activity from polyphenolic compounds
Dosage
- Typical range
- 1–2 grams daily (extract equivalent; adjust based on gingerol content standardization)
- Timing
- With meals for digestive support; 30–60 minutes before travel for nausea
- With food
- Recommended with food to minimize potential gastric irritation
- Duration
- Safe for long-term use; many studies show efficacy with 4–12 weeks of consistent supplementation
- Special populations
- Pregnancy: evidence supports 1–2g daily for morning sickness under medical guidance; avoid in those with bleeding disorders or on anticoagulants without medical supervision
Forms
- Capsule· 70/100
- Powder· 70/100
- Extract· 70/100
Safety
Common side effects
- Mild gastrointestinal upset at higher doses
- Heartburn or acid reflux (occasional)
- Mouth irritation with powdered forms
Contraindications
- Bleeding disorders or concurrent anticoagulant/antiplatelet therapy (minor blood-thinning effects)
- Gallstones (may increase bile flow)
- Acute ulcers or severe GERD (case-dependent; consult physician)
Products containing Supercritical CO2 Ginger Extract (Zingiber officinale)
Top-scoring supplements in our catalog that list Supercritical CO2 Ginger Extract (Zingiber officinale) on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Ginger has strong clinical evidence for nausea (pregnancy-related, post-operative, motion sickness) and moderate evidence for inflammatory and digestive support. Supercritical CO2 extraction concentrates gingerols/shogaols, but evidence base remains consistent with standardized ginger research; grade reflects well-established efficacy without novel mechanism claims.
Grade B: Some human trials support key claims; further confirmation needed.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.