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Herbal Extract

Supercritical CO2 Myrrh Extract (Commiphora myrrha)

Also known as: Myrrh resin extract, Commiphora myrrha extract, Supercritical myrrh, CO2 myrrh extract

C
Evidence

Myrrh is a traditional resin used in Ayurvedic and traditional medicine with emerging evidence for anti-inflammatory and antimicrobial properties. Supercritical CO2 extraction concentrates bioactive compounds including furanodiene, though human clinical evidence remains limited.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

  • Anti-inflammatory support
  • Digestive health
  • Oral health and gum support
  • Traditional immune support
  • Antioxidant support

How it works

  • Furanodiene and other sesquiterpenes may inhibit pro-inflammatory cytokines
  • Antimicrobial activity against oral and digestive pathogens
  • Antioxidant effects via phenolic compounds
  • Potential stimulation of digestive secretions

Dosage

Typical range
300-600 mg daily (of extract)
Timing
With meals or as directed
With food
May be taken with or without food; taking with food may reduce gastrointestinal sensitivity
Duration
Traditional use suggests 4-12 weeks for noticeable effects; no established maximum duration
Special populations
Avoid during pregnancy/breastfeeding; may interact with anticoagulants

Forms

  • Supercritical CO2 extract (capsules)· 70/100
  • Resin extract· 70/100

Safety

Common side effects

  • Gastrointestinal upset or mild diarrhea (rare)
  • Allergic skin reactions in sensitive individuals (very rare)

Contraindications

  • Pregnancy and breastfeeding
  • Bleeding disorders or concurrent anticoagulant therapy
  • Known allergy to Commiphora species

Evidence notes

Myrrh has a long traditional use history and in vitro/animal studies support anti-inflammatory and antimicrobial properties. However, human RCT evidence is limited and sparse. The 4% furanodiene standardization is a quality marker but does not change the overall evidence base. Grade C reflects preliminary/moderate evidence rather than strong clinical trials.

Grade C: Mostly observational or small trials; mechanism is plausible but unproven at scale.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.