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Herbal Extract

Cyracos® (Melissa officinalis) Extract

Also known as: lemon balm extract, Melissa officinalis extract, Cyracos lemon balm, rosmarinic acid extract

B
Evidence

Cyracos is a standardized lemon balm leaf and stem extract containing 7-15% rosmarinic acid, studied primarily for mood support and cognitive relaxation. Clinical evidence supports modest benefits for stress and anxiety, with several human trials demonstrating efficacy.

Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.

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Primary uses

  • Stress and anxiety support
  • Mood support
  • Cognitive relaxation
  • Sleep quality
  • Mental clarity under stress
  • Cognitive performance and focus
  • Mood enhancement

How it works

  • Rosmarinic acid and other polyphenols may modulate GABA signaling and reduce cortisol
  • Antioxidant and neuroprotective effects
  • Potential anxiolytic activity via multiple neurotransmitter pathways

Dosage

Typical range
300-600 mg daily
Timing
Split into 2-3 doses; typically morning and evening
With food
May be taken with or without food; taking with food may reduce any mild GI effects
Duration
Studies typically used 4-12 weeks; benefits may accumulate over 2-4 weeks of consistent use
Special populations
Generally safe for most adults; pregnant and nursing women should consult a healthcare provider

Forms

  • Powder· 70/100
  • Capsule· 70/100
  • Tablet· 70/100
  • Extract· 70/100

Safety

Common side effects

  • Mild gastrointestinal upset (rare)
  • Drowsiness at higher doses
  • Mild headache (uncommon)

Contraindications

  • Avoid if allergic to Lamiaceae family plants
  • Use caution in pregnancy and lactation
  • May potentiate sedatives and CNS depressants

Products containing Cyracos® (Melissa officinalis) Extract

Top-scoring supplements in our catalog that list Cyracos® (Melissa officinalis) Extract on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.

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Evidence notes

Multiple peer-reviewed human clinical trials demonstrate statistically significant improvements in anxiety and stress-related symptoms. The brand-specific Cyracos extract has dedicated research; however, evidence is limited compared to tier-A supplements. Rosmarinic acid standardization ensures batch consistency.

Grade B: Some human trials support key claims; further confirmation needed.

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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.