Herbal Extract
Cyracos® (Melissa officinalis) Extract
Also known as: lemon balm extract, Melissa officinalis extract, Cyracos lemon balm, rosmarinic acid extract
Cyracos is a standardized lemon balm leaf and stem extract containing 7-15% rosmarinic acid, studied primarily for mood support and cognitive relaxation. Clinical evidence supports modest benefits for stress and anxiety, with several human trials demonstrating efficacy.
Last reviewed June 2026 · Evidence graded from peer-reviewed research, not editorial opinion. Educational only — not medical advice.
Every Cyracos® (Melissa officinalis) Extract product we have scored
| # | Product | Score | Per serving |
|---|---|---|---|
| 1 | Life Extension Enhanced Stress Relief | 91 A | $0.70 |
| 2 | Pure Encapsulations Daily Stress Formula | 86 A- | $1.38 |
| 3 | Pure Encapsulations Memory Pro | 85 A- | $2.23 |
| 4 | Pure Encapsulations Best-Rest Formula | 84 A- | $1.23 |
| 5 | Pure Encapsulations Daily Immune | 83 A- | $1.13 |
| 6 | Garden of Life mykind Organics Sleep Well Rest & Refresh | 83 A- | $0.77 |
| 7 | Nested Naturals LUNA Gentle Sleep Supplement | 82 A- | $0.73 |
| 8 | Pure Encapsulations Muscle Cramp/Tension Formula | 81 A- | $0.65 |
| 9 | Olly Ultra Strength Goodbye Stress Softgels | 81 A- | $0.67 |
| 10 | Olly Ultra Strength Sleep Softgels | 81 A- | $0.67 |
| 11 | Vital Nutrients Sleep Aide | 81 A- | $1.95 |
| 12 | Natural Factors Mind Retreat | 81 A- | $0.50 |
Scored on dose accuracy, form, label transparency and third-party testing. Per-serving cost is list price divided by servings per container. No brand pays to be listed or ranked.
Common questions
How much Cyracos® (Melissa officinalis) Extract should I take?
The typical range is 300-600 mg daily. Studies typically used 4-12 weeks; benefits may accumulate over 2-4 weeks of consistent use
When should I take Cyracos® (Melissa officinalis) Extract?
Split into 2-3 doses; typically morning and evening. May be taken with or without food; taking with food may reduce any mild GI effects.
Which form of Cyracos® (Melissa officinalis) Extract is best?
Powder. Other forms in the catalog: Capsule, Tablet, Extract.
Is Cyracos® (Melissa officinalis) Extract safe?
Commonly reported: Mild gastrointestinal upset (rare), Drowsiness at higher doses, Mild headache (uncommon).
Which Cyracos® (Melissa officinalis) Extract supplement scores highest?
Life Extension Enhanced Stress Relief, at 91/100. Scored on dose accuracy, form, label transparency and third-party testing — no brand pays to be listed or ranked.
Primary uses
- Stress and anxiety support
- Mood support
- Cognitive relaxation
- Sleep quality
- Mental clarity under stress
- Cognitive performance and focus
- Mood enhancement
How it works
- Rosmarinic acid and other polyphenols may modulate GABA signaling and reduce cortisol
- Antioxidant and neuroprotective effects
- Potential anxiolytic activity via multiple neurotransmitter pathways
Dosage
- Typical range
- 300-600 mg daily
- Timing
- Split into 2-3 doses; typically morning and evening
- With food
- May be taken with or without food; taking with food may reduce any mild GI effects
- Duration
- Studies typically used 4-12 weeks; benefits may accumulate over 2-4 weeks of consistent use
- Special populations
- Generally safe for most adults; pregnant and nursing women should consult a healthcare provider
Forms
- Powder· 70/100
- Capsule· 70/100
- Tablet· 70/100
- Extract· 70/100
Safety
Common side effects
- Mild gastrointestinal upset (rare)
- Drowsiness at higher doses
- Mild headache (uncommon)
Contraindications
- Avoid if allergic to Lamiaceae family plants
- Use caution in pregnancy and lactation
- May potentiate sedatives and CNS depressants
Products containing Cyracos® (Melissa officinalis) Extract
Top-scoring supplements in our catalog that list Cyracos® (Melissa officinalis) Extract on the label. Each product is graded on Formulate's ingredient-level rubric — dose accuracy, form, transparency, and third-party testing.
Evidence notes
Multiple peer-reviewed human clinical trials demonstrate statistically significant improvements in anxiety and stress-related symptoms. The brand-specific Cyracos extract has dedicated research; however, evidence is limited compared to tier-A supplements. Rosmarinic acid standardization ensures batch consistency.
Grade B: Some human trials support key claims; further confirmation needed.
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Medical disclaimer. This page is educational and does not replace advice from a qualified healthcare provider. Individual needs and risks vary — consult a professional before starting, stopping, or combining supplements, especially if you are pregnant or nursing, taking medication, or managing a health condition.